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The Australian Customer’s V947 Autosampler Vial Order is Completed
The Australian Customer’s V947 Autosampler Vial Order is Completed
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
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Tooling ownership is the first fork in the road
Tooling ownership is the first fork in the road
April 5, 2018
Tooling ownership is the first fork in the road
In 2022 a mid-size contract lab sent me a lot of 2 mL clear glass vials that had passed incoming inspection on every dimensional print: 12.0 mm outer diameter, 32.0 mm height, 6.0 mm neck ID, 11 mm crimp finish. Within four injections on their autosampler, the run died with a “vial not found” error on position 34 of a 100-vial tray. The vials were dimensionally correct. They were also 0.4 mm taller at the shoulder than the previous lot, which is enough to change ho...
Start from the method attribute the vial can actually move, not from the
Start from the method attribute the vial can actually move, not from the
April 5, 2018
Start from the method attribute the vial can actually move, not from the
Lot 22-1147 of 9 mm screw-thread vials arrived with a septum lot number that did not match the certificate in the box, and the first run on it showed a 41% drop in peak area for the 0.5 µg/mL standard compared with the previous week. The analyst’s first instinct was the column. It was the vial. That single event is the most common way a supplier or lot change turns into a revalidation question, and the answer depends on which change actually occurred, not on how nervous the reviewer i...
Tray height tolerance is the variable nobody measures until a run dies
Tray height tolerance is the variable nobody measures until a run dies
April 5, 2018
Tray height tolerance is the variable nobody measures until a run dies
A 12 x 32 mm vial sitting 1.8 mm high in a tray well will pick up cleanly on Monday and fail with a “no sample” error on Thursday after the same tray has been loaded and unloaded eleven times. I have watched that exact drift take down a 96-position run at 3 a.m., and the vial was never the problem. The autosampler pickup error and misalignment that labs blame on “bad vials” is almost always a geometry stack: tray height, gripper tolerance, cap seating, and the small ...